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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKP2
All Species:
18.18
Human Site:
T139
Identified Species:
40
UniProt:
Q13309
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13309
NP_005974.2
424
47761
T139
S
D
E
S
L
W
Q
T
L
D
L
T
G
K
N
Chimpanzee
Pan troglodytes
XP_001147537
379
42771
D98
N
F
P
G
V
S
W
D
S
L
P
D
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001093834
422
47441
T137
S
D
E
S
L
W
Q
T
L
D
L
T
G
K
N
Dog
Lupus familis
XP_546346
749
81658
T464
F
D
E
S
L
W
Q
T
L
D
L
T
G
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0Z3
424
47748
S139
L
D
E
S
L
W
Q
S
L
D
L
A
G
K
N
Rat
Rattus norvegicus
Q9QZH7
276
30442
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007983
443
49750
T160
F
D
E
S
L
W
Q
T
L
D
L
T
C
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036659
499
55071
L194
L
L
D
I
F
K
W
L
P
K
K
T
L
L
R
Honey Bee
Apis mellifera
XP_395497
484
54314
R203
R
D
E
A
L
W
S
R
L
D
L
G
S
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780472
456
51238
R152
Y
D
E
E
L
W
K
R
V
D
L
S
S
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49286
360
39891
S80
W
C
K
K
N
M
N
S
L
V
L
S
L
A
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
91.9
52.3
N.A.
86.3
23.5
N.A.
N.A.
64.1
N.A.
N.A.
N.A.
30
27.8
N.A.
31.3
Protein Similarity:
100
89.3
94.5
54.6
N.A.
92.9
36.7
N.A.
N.A.
74.4
N.A.
N.A.
N.A.
50.9
50.6
N.A.
50
P-Site Identity:
100
0
100
86.6
N.A.
80
0
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
6.6
53.3
N.A.
46.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
86.6
0
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
13.3
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
64
10
0
0
0
0
10
0
64
0
10
0
0
0
% D
% Glu:
0
0
64
10
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
19
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
10
37
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
0
10
10
0
0
10
10
0
0
37
0
% K
% Leu:
19
10
0
0
64
0
0
10
64
10
73
0
19
19
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
10
0
0
0
0
0
0
0
46
% N
% Pro:
0
0
10
0
0
0
0
0
10
0
10
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
19
0
0
0
0
0
28
10
% R
% Ser:
19
0
0
46
0
10
10
19
10
0
0
19
19
0
10
% S
% Thr:
0
0
0
0
0
0
0
37
0
0
0
46
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
10
10
0
0
0
0
10
% V
% Trp:
10
0
0
0
0
64
19
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _